Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645860 | 0.88 | HDAC6 (0.39) | HDAC6HDAC1HDAC2CA14L3MBTL1 | |
| SCHEMBL7651071 | 0.77 | HDAC6 (0.34) | HDAC6HDAC1HDAC2L3MBTL1 | |
| SCHEMBL7648717 | 0.75 | L3MBTL1 (0.44) | HDAC6HDAC1HDAC2L3MBTL1 | |
| SCHEMBL7645723 | 0.74 | L3MBTL1 (0.42) | HDAC6HDAC1HDAC2L3MBTL1 | |
| SCHEMBL7649478 | 0.73 | L3MBTL1 (0.35) | HDAC6HDAC1HDAC2L3MBTL1 | |
| SCHEMBL20383538 | 0.72 | HDAC6 (0.45) | HDAC6HDAC1HDAC2CA14L3MBTL1 | |
| SCHEMBL3012891 | 0.68 | HDAC6 (0.46) | HDAC6HDAC1HDAC2CA14L3MBTL1 | |
| SCHEMBL7649338 | 0.66 | TSHR (0.40) | — | |
| SCHEMBL16363852 | 0.66 | L3MBTL1 (0.39) | L3MBTL1 | |
| SCHEMBL9171625 | 0.66 | HDAC6 (0.50) | HDAC6HDAC1HDAC2CA14L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002008235-A1 | MEDICAMENT FOR ORAL APPLICATION, CONTAINING AMINOPROPYL PHOSPHONIC ACID ESTERS AS AN ACTIVE INGREDIENT | JOMAA PHARMAKA GMBH (DE) | 2002-01-31 | — | — | WO | disclosed |