Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7644146 | 0.82 | TSHR (0.47) | TSHRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7650101 | 0.80 | TSHR (0.34) | TSHRPPARDHSD17B10MGAMGAA | |
| SCHEMBL11203182 | 0.72 | TSHR (0.52) | TSHRPPARDMEN1KMT2AALDH1A1 | |
| SCHEMBL321312 | 0.71 | PPARD (0.54) | TSHRPPARD | |
| SCHEMBL10011234 | 0.71 | TSHR (0.39) | TSHRPPARDHSD17B10MGAMGAA | |
| SCHEMBL1660257 | 0.71 | FAAH (0.32) | — | |
| SCHEMBL10395205 | 0.69 | TSHR (0.60) | TSHRPPARDHSD17B10MGAMGAA | |
| SCHEMBL15951711 | 0.69 | TSHR (0.48) | TSHRALDH1A1LMNA | |
| SCHEMBL28336971 | 0.69 | TSHR (0.48) | TSHRPPARDKMT2AALDH1A1LMNA | |
| SCHEMBL10067496 | 0.69 | TPI1 (0.54) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002008235-A1 | MEDICAMENT FOR ORAL APPLICATION, CONTAINING AMINOPROPYL PHOSPHONIC ACID ESTERS AS AN ACTIVE INGREDIENT | JOMAA PHARMAKA GMBH (DE) | 2002-01-31 | — | — | WO | disclosed |