Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9908396 | 0.82 | MEN1 (0.38) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL9908407 | 0.81 | MEN1 (0.35) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL11596492 | 0.78 | OPRK1 (0.37) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL13706699 | 0.78 | OPRK1 (0.39) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL32689229 | 0.76 | MEN1 (0.34) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL14694312 | 0.75 | MEN1 (0.32) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL21626126 | 0.74 | OPRK1 (0.37) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL112908 | 0.74 | OPRK1 (0.37) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL3332068 | 0.73 | — | — | |
| SCHEMBL3332078 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002051395-A1 | TREATMENT OF NEURODEGENERATIVE DISEASES | CODON PHARMACEUTICALS, INC. (US) | 2002-07-04 | — | — | WO | claimed |
| WO-1998055085-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | CODON PHARMACEUTICALS, INC. (US) | 1998-12-10 | — | — | WO | claimed |