SCHEMBL7647891

SCHEMBL7647891

CC(C)CC(=O)Nc1ccccc1C(C)C

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.58
POLB P06746 2/20 0.57
GAA P10253 2/20 0.56
NLRP3 Q96P20 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.54
RAB9A P51151 1/20 0.54
LMNA P02545 3/20 0.53
HPGD P15428 1/20 0.53
MAPT P10636 3/20 0.52
MEN1 O00255 2/20 0.52
ALDH1A1 P00352 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
RECQL P46063 2/20 0.50
PTPN1 P18031 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979145 0.87 KMT2A (0.56) KMT2APOLBNLRP3LMNAMAPT
SCHEMBL9979203 0.85 KMT2A (0.55) KMT2APOLBNLRP3LMNAMAPT
SCHEMBL10695522 0.84 KMT2A (0.60) KMT2APOLBNLRP3LMNAMAPT
SCHEMBL13652637 0.84 KMT2A (0.60) KMT2APOLBNLRP3SMN1; SMN2RAB9A
SCHEMBL31337280 0.83 KMT2A (0.58) KMT2APOLBNLRP3LMNAMAPT
SCHEMBL7769522 0.83 SMN1; SMN2 (0.68) KMT2APOLBNLRP3SMN1; SMN2LMNA
SCHEMBL3978692 0.83 KMT2A (0.58) KMT2APOLBNLRP3LMNAMAPT
SCHEMBL27713876 0.81 POLB (0.59) KMT2APOLBGAASMN1; SMN2RAB9A
SCHEMBL4960066 0.81 HPGD (0.62) POLBGAASMN1; SMN2RAB9ALMNA
SCHEMBL2341773 0.80 MAPT (0.58) KMT2ANLRP3RAB9AMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115385955-A Tetrabiarylphosphine ligands and transition metal complexes thereof 东莞市均成高新材料有限公司 2022-11-25 CN disclosed
US-20020065315-A1 Ion channel modulating agents POSEIDON PHARMACEUTICALS A/S (DK) 2002-05-30 US disclosed
EP-1178963-A1 ION CHANNEL MODULATING AGENTS NEUROSEARCH A/S (DK) 2002-02-13 EP disclosed
WO-2000069823-A1 ION CHANNEL MODULATING AGENTS NEUROSEARCH A/S (DK) 2000-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020065315-A1 Ion channel modulating agents KCNN1, KCNN3, KCNN2 KMT2A 1603/4885POLB 4808/4885GAA 2260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.