Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342825 | 0.87 | LMNA (0.54) | CYP1A2MEN1KMT2ALMNABLM | |
| SCHEMBL7645645 | 0.87 | LMNA (0.54) | CYP1A2LMNABLMCYP3A4NFKB1 | |
| SCHEMBL6354148 | 0.68 | CYP1A2 (0.42) | CYP1A2MEN1KMT2ALMNABLM | |
| Hydrochloric Acid SCHEMBL9336310 | 0.67 | LMNA (0.41) | CYP1A2MEN1KMT2ALMNABLM | |
| SCHEMBL2353070 | 0.66 | CYP1A2 (0.57) | CYP1A2MEN1KMT2ALMNABLM | |
| SCHEMBL5140906 | 0.66 | GABBR2 (0.56) | CYP1A2MEN1KMT2ALMNABLM | |
| SCHEMBL6351937 | 0.66 | GABBR2 (0.50) | CYP1A2MEN1KMT2ALMNABLM | |
| SCHEMBL6354585 | 0.65 | CYP1A2 (0.55) | CYP1A2MEN1KMT2ALMNABLM | |
| SCHEMBL6360302 | 0.65 | GABBR2 (0.54) | CYP1A2MEN1KMT2ALMNABLM | |
| Hydrochloric Acid SCHEMBL9417053 | 0.64 | GABBR2 (0.48) | CYP1A2MEN1KMT2ALMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | claimed |