Pyrrole

Pyrrole

SCHEMBL7648947

NC(=O)c1cc2ccccc2[nH]1.c1cc[nH]c1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.61
ALDH1A1 P00352 2/20 0.61
GAA P10253 1/20 0.61
MAPK1 P28482 1/20 0.61
FLT3 P36888 4/20 0.61
HSD17B10 Q99714 2/20 0.59
MAPT P10636 1/20 0.59
DAO P14920 1/20 0.59
HPGD P15428 1/20 0.59
SRD5A2 P31213 1/20 0.59
IDO1 P14902 1/20 0.54
HRH4 Q9H3N8 4/20 0.52
LMNA P02545 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
PDGFRB P09619 2/20 0.50
PDGFRA P16234 2/20 0.50
HRH3 Q9Y5N1 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL118686 0.91 FLT3 (0.71) KDM4EALDH1A1GAAMAPK1FLT3
SCHEMBL29362757 0.91 FLT3 (0.71) KDM4EALDH1A1GAAMAPK1FLT3
Water SCHEMBL30277651 0.90 FLT3 (0.69) KDM4EALDH1A1GAAMAPK1FLT3
Hydrochloric Acid SCHEMBL20569802 0.90 FLT3 (0.69) KDM4EALDH1A1GAAMAPK1FLT3
Hydrochloric Acid SCHEMBL28280255 0.90 FLT3 (0.69) KDM4EALDH1A1GAAMAPK1FLT3
Bromide SCHEMBL6056708 0.90 FLT3 (0.69) KDM4EALDH1A1GAAMAPK1FLT3
Hydrochloric Acid SCHEMBL30164222 0.90 FLT3 (0.69) KDM4EALDH1A1GAAMAPK1FLT3
Hydrochloric Acid SCHEMBL16463892 0.90 FLT3 (0.69) KDM4EALDH1A1GAAMAPK1FLT3
Hydrochloric Acid SCHEMBL30071329 0.90 FLT3 (0.69) KDM4EALDH1A1GAAMAPK1FLT3
Indole SCHEMBL28758598 0.84 FLT3 (0.57) KDM4EALDH1A1GAAMAPK1FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6486308-B2 NUCLEOTIDE SEQUENCE BINDING PARTICLES; FOR USE AS THERAPEUTIC AND DIAGNOSTIC TOOLS EPOCH BIOSCIENCES, INC. 2002-11-26 US disclosed