SCHEMBL7649239

SCHEMBL7649239

CC(C)(C)c1cc(CC(Cc2cc(C(C)(C)C)cc(C(C)(C)C)c2O)(C(=O)O)C(=O)O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLRA3 O75311 1/20 0.43
GLRB P48167 1/20 0.43
ALDH1A1 P00352 4/20 0.43
MAPK1 P28482 3/20 0.43
NPSR1 Q6W5P4 3/20 0.43
GAA P10253 2/20 0.43
XBP1 P17861 1/20 0.43
HTT P42858 1/20 0.43
NR5A2 O00482 1/20 0.43
NR5A1 Q13285 1/20 0.43
CYP2C19 P33261 6/20 0.42
CYP2C9 P11712 5/20 0.42
CYP1A2 P05177 4/20 0.42
CYP3A4 P08684 3/20 0.42
TSHR P16473 3/20 0.42
HSPA5 P11021 2/20 0.41
HIF1A Q16665 5/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALOX5 P09917 1/20 0.39
PTGS2 P35354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29966261 1.00 GLRA3 (0.43) GLRA3GLRBALDH1A1MAPK1NPSR1
SCHEMBL27968591 0.90 CYP1A2 (0.45) GLRA3GLRBALDH1A1MAPK1NPSR1
SCHEMBL1719554 0.87 NR5A2 (0.48) GLRA3GLRBALDH1A1MAPK1NPSR1
SCHEMBL17500076 0.81 ALDH1A1 (0.48) ALDH1A1MAPK1NPSR1GAAXBP1
SCHEMBL11572741 0.80 NR5A2 (0.42) NR5A2NR5A1CYP2C19CYP2C9CYP1A2
SCHEMBL6568740 0.80 NR5A2 (0.42) NR5A2NR5A1CYP2C19CYP2C9CYP1A2
SCHEMBL5605119 0.80 RXRA (0.48) GLRA3GLRBALDH1A1MAPK1NPSR1
SCHEMBL28799870 0.79 GLRA3 (0.42) GLRA3GLRBALDH1A1MAPK1NPSR1
SCHEMBL29404283 0.79 HSPA5 (0.55) GLRA3GLRBALDH1A1MAPK1NPSR1
SCHEMBL8028498 0.79 HSPA5 (0.55) GLRA3GLRBALDH1A1MAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3194482-B1 USE OF PHOSPHOROUS-CONTAINING ORGANIC OXYIMIDES AS FLAME RETARDANTS FOR PLASTICS, FLAME-RETARDANT PLASTIC COMPOSITIONS, METHOD FOR THE PRODUCTION THEREOF, MOULDED PART, PAINT AND COATINGS FRAUNHOFER GES FORSCHUNG (DE) 2024-05-08 EP disclosed
EP-3710424-B1 COMPOUNDS HAVING A STABILIZING EFFECT, METHOD FOR PRODUCING SAID COMPOUNDS, COMPOSITION CONTAINING SAID STABILIZING COMPOUNDS, METHOD FOR STABILIZING AN ORGANIC COMPONENT, AND USE OF STABILIZING COMPOUNDS FRAUNHOFER GES FORSCHUNG (DE) 2024-01-03 EP disclosed
EP-3947540-B1 METHOD FOR STABILIZING THERMOPLASTIC RECYCLATES, STABILIZED PLASTIC COMPOSITIONS, AND MOLDING COMPOUNDS AND MOLDED PARTS PRODUCED THEREFROM FRAUNHOFER GES FORSCHUNG (DE) 2023-08-16 EP disclosed
EP-3924411-A1 FLAME RETARDANT MIXTURE FOR THERMOPLASTIC POLYMERS Clariant International Ltd. (CH) 2021-12-22 EP disclosed
EP-3911696-A1 FLAME RETARDANT MIXTURE Clariant International Ltd (CH) 2021-11-24 EP disclosed
WO-2020165017-A1 FLAME RETARDANT MIXTURE FOR THERMOPLASTIC POLYMERS CLARIANT PLASTICS & COATINGS LTD (CH) 2020-08-20 WO disclosed
WO-2020147943-A1 FLAME RETARDANT MIXTURE CLARIANT PLASTICS & COATINGS LTD (CH) 2020-07-23 WO disclosed
CN-106574090-B 3- phenylbenzofuran -2- ketone diphosphorous acid ester derivant as stabilizer 巴斯夫欧洲公司 2019-11-19 CN disclosed
CN-105399730-B Sterically hindered amine stabilizer 巴斯夫欧洲公司 2019-02-22 CN disclosed
CN-108699288-A Flame-retardant polyamide composition 科莱恩塑料和涂料有限公司 2018-10-23 CN disclosed
WO-2012153260-A1 MIXTURE OF STERICALLY HINDERED AMINES FOR POLYMER STABILIZATION 3V SIGMA S.P.A. (IT) 2012-11-15 WO disclosed
CN-101189318-B Reversibly thermochromic compositions CIBA SC HOLDING AG 2012-06-20 CN disclosed
CN-102066451-A Hyperbranched polymers and oligomers containing terminal amino groups as curing agents for epoxy resins BASF SE 2011-05-18 CN disclosed
CN-101189318-A Reversibly thermochromic compositions CIBA SC HOLDING AG (CH) 2008-05-28 CN disclosed
CN-101119756-A Absorbent structure with improved water-absorbing material PROCTER & GAMBLE (US) 2008-02-06 CN disclosed
CN-101115508-A Absorbent structure with improved water-absorbing material PROCTER & GAMBLE (US) 2008-01-30 CN disclosed
EP-1263856-A1 STABILIZER COMPOSITION BASF AKTIENGESELLSCHAFT (DE) 2002-12-11 EP disclosed
WO-2001057122-A1 STABILIZER COMPOSITION BASF AKTIENGESELLSCHAFT (DE) 2001-08-09 WO disclosed
US-5985964-A LUBRICANTS AND FATTY ACID SALTS WITCO VINYL ADDITIVES GMBH (DE) 1999-11-16 US disclosed
US-4649221-A POLYOLEFINS, STABILIZERS, DISCOLORATION INHIBITION CIBA-GEIGY CORPORATION (US) 1987-03-10 US disclosed