SCHEMBL7649265

SCHEMBL7649265

CCC(O)CCc1ccc(-c2cc(CCc3ccc(CO)c(CO)c3)sc2C)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
VDR P11473 2/20 0.38
STAT3 P40763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7648316 0.85 VDR (0.38) VDRSTAT3
SCHEMBL7615205 0.84 VDR (0.52) VDRSTAT3
SCHEMBL7649262 0.82 VDR (0.38) VDR
SCHEMBL7647800 0.80 VDR (0.39) VDRSTAT3
SCHEMBL6565142 0.80 VDR (0.61) VDR
SCHEMBL7606177 0.76 VDR (0.54) VDR
SCHEMBL7607763 0.75 VDR (0.46) VDRSTAT3
SCHEMBL7610506 0.74 VDR (0.43) VDR
SCHEMBL7606753 0.73 VDR (0.35) VDRSTAT3
SCHEMBL7608507 0.72 VDR (0.34) VDRSTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1235777-A2 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2002-09-04 EP disclosed
WO-2001038303-A2 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2001-05-31 WO disclosed