Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308290 | 0.84 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL7355501 | 0.84 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL27425940 | 0.84 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL234454 | 0.84 | LMNA (0.62) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL10980848 | 0.83 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL16945695 | 0.81 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL8891764 | 0.81 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL11388818 | 0.81 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL10508938 | 0.81 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL550351 | 0.80 | NPC1 (0.60) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479265-B1 | Catalytic antibodies which hydrolyze primary amides and methods for eliciting and use of such antibodies | IGEN INTERNATIONAL, INC. | 2002-11-12 | — | — | US | disclosed |
| US-5900237-A | GENETIC ENGINEERING | IGEN INTERNATIONAL, INC. (US) | 1999-05-04 | — | — | US | disclosed |
| EP-0696318-A4 | CATALYTIC ANTIBODIES WHICH HYDROLYZE PRIMARY AMIDES AND METHODS FOR ELICITING SUCH ANTIBODIES | IGEN INC (US) | 1998-04-15 | — | — | EP | disclosed |
| EP-0696318-A1 | CATALYTIC ANTIBODIES WHICH HYDROLYZE PRIMARY AMIDES AND METHODS FOR ELICITING SUCH ANTIBODIES | IGEN, INC. (a California corporation) (US) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025573-A1 | CATALYTIC ANTIBODIES WHICH HYDROLYZE PRIMARY AMIDES AND METHODS FOR ELICITING SUCH ANTIBODIES | IGEN, INC. (US) | 1994-11-10 | — | — | WO | disclosed |
| EP-0538374-A4 | ASPARTIC PROTEASE INHIBITORS | — | 1993-05-19 | — | — | EP | disclosed |
| EP-0538374-A1 | ASPARTIC PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000954-A1 | ASPARTIC PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |