Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 5/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652786 | 0.84 | IL6ST (0.41) | IL6STPPARAABCB1IDH1LTB4R | |
| SCHEMBL7655411 | 0.82 | PPARA (0.40) | IL6STPPARAABCB1SCD5ALDH1A1 | |
| SCHEMBL7661064 | 0.81 | IL6ST (0.41) | IL6STPPARAABCB1IDH1LTB4R | |
| SCHEMBL21911110 | 0.78 | IL6ST (0.47) | IL6STPPARAABCB1IDH1 | |
| SCHEMBL23998195 | 0.78 | IL6ST (0.47) | IL6STPPARAABCB1IDH1 | |
| SCHEMBL16985553 | 0.76 | PPARA (0.49) | IL6STPPARAIDH1ALDH1A1 | |
| SCHEMBL18985089 | 0.76 | PPARA (0.49) | IL6STPPARAIDH1ALDH1A1 | |
| SCHEMBL19018653 | 0.76 | IL6ST (0.52) | IL6STPPARAIDH1 | |
| SCHEMBL5500880 | 0.76 | IL6ST (0.52) | IL6STPPARAIDH1 | |
| SCHEMBL7797511 | 0.76 | IL6ST (0.52) | IL6STPPARAIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448409-B1 | ACYLATION OF AN 2-OXAZOLIDINESELONE WITH AN ALKYL ACYLHALIDE AND HYDROXYLATION WITH AN ALDEHYDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-09-10 | — | — | US | disclosed |