Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23461757 | 0.87 | IL6ST (0.52) | IL6STPPARAIDH1PPARG | |
| SCHEMBL15925288 | 0.87 | IL6ST (0.52) | IL6STPPARAIDH1PPARG | |
| SCHEMBL27133027 | 0.87 | IL6ST (0.52) | IL6STPPARAIDH1PPARG | |
| SCHEMBL15925285 | 0.87 | IL6ST (0.52) | IL6STPPARAIDH1PPARG | |
| SCHEMBL27133026 | 0.87 | IL6ST (0.52) | IL6STPPARAIDH1PPARG | |
| SCHEMBL7655411 | 0.85 | PPARA (0.40) | IL6STPPARAABCB1PPARGALDH1A1 | |
| SCHEMBL7649458 | 0.84 | IL6ST (0.39) | IL6STPPARAABCB1LTB4RLTB4R2 | |
| SCHEMBL7661064 | 0.82 | IL6ST (0.41) | IL6STPPARAABCB1LTB4RLTB4R2 | |
| SCHEMBL24418522 | 0.78 | IL6ST (0.52) | IL6STPPARAABCB1IDH1 | |
| SCHEMBL7657037 | 0.78 | ALDH1A1 (0.42) | PPARAABCB1LTB4RLTB4R2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448409-B1 | ACYLATION OF AN 2-OXAZOLIDINESELONE WITH AN ALKYL ACYLHALIDE AND HYDROXYLATION WITH AN ALDEHYDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-09-10 | — | — | US | disclosed |