Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952443 | 0.89 | BRD4 (0.46) | NPC1RAB9ABRD4CREBBPPARP1 | |
| SCHEMBL7656006 | 0.87 | KDM4E (0.42) | NPC1RAB9ABRD4CREBBPPARP1 | |
| SCHEMBL29828622 | 0.87 | CHEK1 (0.48) | NPC1RAB9ABRD4CREBBPMMP2 | |
| SCHEMBL6945277 | 0.87 | CHEK1 (0.48) | NPC1RAB9ABRD4CREBBPMMP2 | |
| SCHEMBL7653156 | 0.85 | ALDH1A1 (0.42) | NPC1RAB9ABRD4CREBBPPARP1 | |
| SCHEMBL7650912 | 0.85 | NPC1 (0.40) | NPC1RAB9ABRD4CREBBPPARP1 | |
| SCHEMBL529009 | 0.85 | RAB9A (0.48) | NPC1RAB9ABRD4CREBBPHTR6 | |
| SCHEMBL7657249 | 0.84 | NPC1 (0.39) | NPC1RAB9ABRD4CREBBPPARP1 | |
| SCHEMBL7649497 | 0.84 | NPC1 (0.41) | NPC1RAB9ACYP1A2CYP2C9MMP2 | |
| SCHEMBL7654820 | 0.83 | ALDH1A1 (0.50) | NPC1RAB9ABRD4CREBBPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |