Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652663 | 0.98 | SPHK1 (0.46) | SPHK1FFAR4SPHK2SIGMAR1 | |
| SCHEMBL7651816 | 0.95 | SPHK1 (0.47) | SPHK1FFAR4SPHK2SIGMAR1 | |
| SCHEMBL7647363 | 0.93 | SPHK1 (0.50) | SPHK1FFAR4SPHK2SIGMAR1 | |
| SCHEMBL7654715 | 0.93 | SPHK1 (0.49) | SPHK1FFAR4SPHK2SIGMAR1 | |
| SCHEMBL7650285 | 0.91 | SPHK1 (0.51) | SPHK1FFAR4SPHK2SIGMAR1 | |
| SCHEMBL5544467 | 0.89 | SPHK1 (0.40) | SPHK1KCNH2HRH3HTR2CHTR2B | |
| SCHEMBL3146239 | 0.86 | SPHK1 (0.41) | SPHK1FFAR4HTR2CHTR2B | |
| SCHEMBL20793673 | 0.81 | SPHK1 (0.45) | SPHK1KCNH2HRH3FFAR4SPHK2 | |
| SCHEMBL21152607 | 0.81 | SPHK1 (0.45) | SPHK1KCNH2HRH3FFAR4SPHK2 | |
| SCHEMBL11282060 | 0.81 | SPHK1 (0.45) | SPHK1KCNH2HRH3FFAR4SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149214-C | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | ������������ʽ���� | 2004-05-12 | — | — | CN | disclosed |
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| CN-1293674-A | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2001-05-02 | — | — | CN | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |