Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649179 | 0.95 | HRH1 (0.39) | HRH1SLC2A1SLC6A4RIPK1SLC6A2 | |
| SCHEMBL7654241 | 0.94 | HRH1 (0.38) | HRH1SLC2A1SLC6A4RIPK1SLC6A2 | |
| SCHEMBL7650237 | 0.90 | HRH1 (0.42) | HRH1SLC2A1SLC6A4RIPK1SLC6A2 | |
| SCHEMBL7648320 | 0.83 | HRH1 (0.41) | HRH1SLC6A4RIPK1SLC6A2TTR | |
| SCHEMBL4447070 | 0.80 | HRH1 (0.64) | HRH1SLC6A4LTA4H | |
| SCHEMBL7646958 | 0.80 | HRH1 (0.62) | HRH1SLC6A4RIPK1SLC6A2LTA4H | |
| SCHEMBL4448343 | 0.78 | TTR (0.51) | HRH1SLC6A4RIPK1SLC6A2TTR | |
| SCHEMBL536544 | 0.76 | LTA4H (0.58) | HRH1TTRLTA4HTSHRCYP2C9 | |
| SCHEMBL7652659 | 0.76 | NCEH1 (0.43) | HRH1SLC2A1SLC6A4 | |
| SCHEMBL15345849 | 0.76 | HRH1 (0.49) | HRH1SLC6A4RIPK1SLC6A2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |