SCHEMBL7646958

SCHEMBL7646958

[CH2]CCCc1ccccc1Oc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 1/20 0.62
SLC6A4 P31645 7/20 0.51
SLC6A2 P23975 4/20 0.51
RIPK1 Q13546 1/20 0.51
CYP19A1 P11511 1/20 0.43
FFAR1 O14842 1/20 0.42
HTR2A P28223 4/20 0.41
SLC6A3 Q01959 3/20 0.40
LTA4H P09960 1/20 0.39
TSHR P16473 1/20 0.39
MAOA P21397 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5535030 0.95 HRH1 (0.61) HRH1SLC6A4SLC6A2RIPK1CYP19A1
SCHEMBL7653319 0.93 HRH1 (0.59) HRH1SLC6A4SLC6A2RIPK1CYP19A1
SCHEMBL5545669 0.89 HRH1 (0.67) HRH1SLC6A4SLC6A2RIPK1CYP19A1
SCHEMBL2676995 0.81 HRH1 (0.79) HRH1SLC6A4SLC6A2RIPK1CYP19A1
SCHEMBL29580562 0.81 HRH1 (0.62) HRH1SLC6A4SLC6A2RIPK1HTR2A
SCHEMBL6186762 0.81 HRH1 (0.62) HRH1SLC6A4SLC6A2RIPK1HTR2A
SCHEMBL6503487 0.81 HRH1 (0.62) HRH1SLC6A4SLC6A2RIPK1CYP19A1
SCHEMBL5389689 0.81 HRH1 (0.62) HRH1SLC6A4SLC6A2RIPK1CYP19A1
SCHEMBL1070099 0.81 HRH1 (0.62) HRH1SLC6A4SLC6A2RIPK1CYP19A1
SCHEMBL9480066 0.81 THRA (0.40) HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same KURARAY CO., LTD. (JP) 2024-07-09 US disclosed
US-11981763-B2 Resin composition for stereolithographic modeling KURARAY NORITAKE DENTAL INC. (JP) 2024-05-14 US disclosed
EP-3900693-B1 USE OF A RESIN COMPOSITION KURARAY NORITAKE DENTAL INC (JP) 2024-03-20 EP disclosed
US-11814454-B2 Curable composition, and resin composition for stereolithography prepared therefrom KURARAY CO., LTD. (JP) 2023-11-14 US disclosed
EP-4268792-A1 ADHESIVE COMPOSITION FOR PHOTOFABRICATION ARTICLES Kuraray Noritake Dental Inc. (JP) 2023-11-01 EP disclosed
WO-2023190931-A1 RESIN COMPOSITION FOR STEREOLITHOGRAPHY クラレノリタケデンタル株式会社 2023-10-05 WO disclosed
WO-2023182514-A1 ADHESIVE COMPOSITION FOR STEREOLITHOGRAPHIC ARTICLE AND NON-STEREOLITHOGRAPHIC ARTICLE クラレノリタケデンタル株式会社 2023-09-28 WO disclosed
US-20230210728-A1 ENERGY RAY-CURABLE COATING MATERIAL FOR THREE-DIMENSIONAL SHAPED ARTICLES, ENERGY RAY-CURABLE MATERIAL KIT FOR THREE-DIMENSIONAL SHAPING INCLUDING SAME, THREE-DIMENSIONAL SHAPED ARTICLE USING SAME, AND METHOD OF PRODUCTION THEREOF KURARAY NORITAKE DENTAL INC. (JP) 2023-07-06 US disclosed
WO-2023127934-A1 ENERGY-RAY-CURABLE COMPOSITION FOR THREE-DIMENSIONAL SHAPING USE, DENTAL STRUCTURE, MOUTHPIECE, TEETH-STRAIGHTENING MOUTHPIECE, AND METHOD FOR PRODUCING DENTAL STRUCTURE クラレノリタケデンタル株式会社 2023-07-06 WO disclosed
WO-2023120610-A1 DENTAL CURABLE COMPOSITION クラレノリタケデンタル株式会社 2023-06-29 WO disclosed
EP-3981810-A1 RESIN COMPOSITION FOR OPTICAL SHAPING Kuraray Noritake Dental Inc. (JP) 2022-04-13 EP disclosed
US-20220041777-A1 RESIN COMPOSITION FOR OPTICAL SHAPING KURARAY NORITAKE DENTAL INC. (JP) 2022-02-10 US disclosed
US-20210340304-A1 RESIN COMPOSITION FOR OPTICAL SHAPING KURARAY NORITAKE DENTALI INC. (JP) 2021-11-04 US disclosed
EP-3900693-A1 RESIN COMPOSITION FOR OPTICAL MOLDING Kuraray Noritake Dental Inc. (JP) 2021-10-27 EP disclosed
EP-3862373-A1 RESIN COMPOSITION FOR OPTICAL SHAPING Kuraray Noritake Dental Inc. (JP) 2021-08-11 EP disclosed
WO-2021132699-A1 ENERGY RAY-CURABLE COATING MATERIAL FOR THREE-DIMENSIONAL MOLDING, ENERGY RAY-CURABLE MATERIAL KIT FOR THREE-DIMENSIONAL MOLDING CONTAINING SAID SAME, THREE-DIMENSIONAL MOLDED PRODUCT OBTAINED USING SAME, AND METHOD FOR PRODUCING SAME クラレノリタケデンタル株式会社 2021-07-01 WO disclosed
WO-2021066073-A1 RESIN COMPOSITION FOR STEREOLITHOGRAPHY クラレノリタケデンタル株式会社 2021-04-08 WO disclosed
CN-1149214-C Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient ������������ʽ���� 2004-05-12 CN disclosed
US-6492364-B1 Triazolo and derivatives as chemokine inhibitors TORAY INDUSTRIES, INC. (JP) 2002-12-10 US disclosed
EP-1067130-A1 TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT TORAY INDUSTRIES, INC. (JP) 2001-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11814454-B2 Curable composition, and resin composition for stereolithography prepared therefrom WASF2, COPE, ARCN1 HRH1 3453/4885SLC6A4 4523/4885SLC6A2 4778/4885
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same ARL1, ASH2L, VCL HRH1 2443/4885SLC6A4 4503/4885SLC6A2 4818/4885
US-20230210728-A1 ENERGY RAY-CURABLE COATING MATERIAL FOR THREE-DIMENSIONAL SHAPED ARTICLES, ENERGY RAY-CURABLE MATERIAL KIT FOR THREE-DIMENSIONAL SHAPING INCLUDING SAME, THREE-DIMENSIONAL SHAPED ARTICLE USING SAME, AND METHOD OF PRODUCTION THEREOF KIT, SETD7, SETDB1 HRH1 3785/4885SLC6A4 4567/4885SLC6A2 4776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.