Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648876 | 0.99 | SIGMAR1 (0.40) | SIGMAR1CXCR4BCHESLC22A12ADRA1D | |
| SCHEMBL7654475 | 0.99 | SIGMAR1 (0.39) | SIGMAR1CXCR4BCHESLC22A12DRD2 | |
| SCHEMBL7650825 | 0.97 | SIGMAR1 (0.38) | SIGMAR1CXCR4BCHESLC22A12HTR6 | |
| SCHEMBL7649392 | 0.94 | CXCR4 (0.40) | SIGMAR1CXCR4BCHESLC22A12ADRA1D | |
| SCHEMBL7648255 | 0.93 | CXCR4 (0.38) | SIGMAR1CXCR4BCHESLC22A12HTR6 | |
| SCHEMBL7649198 | 0.88 | CXCR4 (0.39) | SIGMAR1CXCR4BCHESLC22A12HTR6 | |
| SCHEMBL7648103 | 0.86 | SLC22A12 (0.38) | SIGMAR1CXCR4BCHESLC22A12HTR6 | |
| SCHEMBL27508764 | 0.84 | BCHE (0.46) | SIGMAR1CXCR4BCHEDRD2SLC6A4 | |
| SCHEMBL27545615 | 0.82 | BCHE (0.44) | SIGMAR1CXCR4BCHESLC22A12DRD2 | |
| SCHEMBL7652944 | 0.82 | NAAA (0.37) | SIGMAR1CXCR4PTGDR2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149214-C | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | ������������ʽ���� | 2004-05-12 | — | — | CN | disclosed |
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| CN-1293674-A | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2001-05-02 | — | — | CN | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |