Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148236 | 0.83 | HRH3 (0.37) | KMT2AMEN1SLC6A3CYP2C19HRH3 | |
| SCHEMBL2356015 | 0.78 | TDP1 (0.39) | KMT2AMAPTMEN1NPSR1KDM4E | |
| SCHEMBL8605624 | 0.77 | TP53 (0.42) | KMT2AMAPTMEN1KDM4ETSHR | |
| SCHEMBL7027544 | 0.76 | ELANE (0.41) | KMT2AMEN1HSD17B10 | |
| Alcohol SCHEMBL27455943 | 0.75 | TDP1 (0.35) | KMT2AMEN1KDM4ETSHRHPGD | |
| SCHEMBL8188494 | 0.75 | KMT2A (0.49) | L3MBTL1KMT2AMAPTMEN1NPSR1 | |
| SCHEMBL6501299 | 0.72 | CA4 (0.34) | KDM4ETSHRHSD17B10SLC6A2SLC6A4 | |
| SCHEMBL12227559 | 0.67 | KMT2A (0.33) | L3MBTL1KMT2AMEN1TSHRHPGD | |
| SCHEMBL2091231 | 0.67 | L3MBTL1 (0.42) | L3MBTL1KMT2AMAPTMEN1NPSR1 | |
| SCHEMBL6544243 | 0.67 | TSHR (0.44) | L3MBTL1KMT2AMAPTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966489-A4 | IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION | UNIV CARNEGIE MELLON (US) | 2002-03-06 | — | — | EP | disclosed |
| EP-0966489-A1 | IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION | CARNEGIE MELLON UNIVERSITY (US) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998040415-A1 | IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION | CARNEGIE MELLON UNIVERSITY (US) | 1998-09-17 | — | — | WO | disclosed |