Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605624 | 0.81 | TP53 (0.42) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL7651087 | 0.78 | L3MBTL1 (0.40) | CYP2D6CYP2C19MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7027544 | 0.77 | ELANE (0.41) | MEN1KMT2AALDH1A1LMNAP2RX7 | |
| SCHEMBL6501299 | 0.76 | CA4 (0.34) | TSHRKDM4EMAPK1SLC6A2SLC6A4 | |
| SCHEMBL8148236 | 0.74 | HRH3 (0.37) | CYP2D6CYP2C19MEN1KMT2AALDH1A1 | |
| Alcohol SCHEMBL27455943 | 0.72 | TDP1 (0.35) | TDP1CYP2D6MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6245335 | 0.72 | TDP1 (0.50) | TDP1CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL11587461 | 0.70 | TDP1 (0.38) | TDP1CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL3158948 | 0.69 | TDP1 (0.51) | TDP1CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL28704692 | 0.69 | HTT (0.46) | TDP1CYP2C19MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349523-A1 | WATER FLUX POLYMER MEMBRANES | Arkema, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-2231729-A1 | ACRYLIC-BASED RUBBER MODIFIED THERMOSET COMPOSITION | Arkema, Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2010051150-A1 | WATER FLUX POLYMER MEMBRANES | ARKEMA INC. (US) | 2010-05-06 | — | — | WO | disclosed |
| EP-2097140-A2 | POLYMER ENCAPSULATION AND/OR BINDING | Arkema Inc. (US) | 2009-09-09 | — | — | EP | disclosed |
| WO-2009076069-A1 | ACRYLIC-BASED RUBBER MODIFIED THERMOSET COMPOSITION | ARKEMA INC. (US) | 2009-06-18 | — | — | WO | disclosed |
| WO-2009074532-A1 | ELASTOMERIC FLEXIBILIZER FOR THERMOSETS | ARKEMA FRANCE (FR) | 2009-06-18 | — | — | WO | disclosed |
| EP-2027208-A2 | AMPHIPHILIC BLOCK COPOLYMERS | Arkema Inc. (US) | 2009-02-25 | — | — | EP | disclosed |
| EP-2019747-A1 | IMPACT MODIFIER COMPOSITION FOR TRANSPARENT THERMOPLASTICS | Arkema Inc. (US) | 2009-02-04 | — | — | EP | disclosed |
| WO-2008079677-A2 | POLYMER ENCAPSULATION AND/OR BINDING | ARKEMA INC. (US) | 2008-07-03 | — | — | WO | disclosed |
| WO-2007140225-A2 | AMPHIPHILIC BLOCK COPOLYMERS | ARKEMA INC. (US) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007140101-A1 | IMPACT MODIFIER COMPOSITION FOR TRANSPARENT THERMOPLASTICS | ARKEMA INC. (US) | 2007-12-06 | — | — | WO | disclosed |
| EP-1725637-A1 | CONTROLLED RADICAL ACRYLIC COPOLYMER THICKENERS | Arkema Inc. (US) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005056739-A1 | CONTROLLED RADICAL ACRYLIC COPOLYMER THICKENERS | ARKEMA INC. (US) | 2005-06-23 | — | — | WO | disclosed |
| EP-1311472-A2 | METHOD FOR PREPARING ALKOXYAMINES FROM NITROXIDES | Atofina (FR) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002012149-A2 | METHOD FOR PREPARING ALKOXYAMINES FROM NITROXIDES | ATOFINA (FR) | 2002-02-14 | — | — | WO | disclosed |
| EP-1153030-A1 | ALKOXYAMINES ISSUES DE NITROXIDES SS-PHOSPHORES | Atofina (FR) | 2001-11-14 | — | — | EP | disclosed |
| CN-1313847-A | Method for preparing alkoxyamines from nitroxides | ATOCHEM ELF SA (FR) | 2001-09-19 | — | — | CN | disclosed |
| WO-2000049027-A1 | ALKOXYAMINES ISSUES DE NITROXIDES SS-PHOSPHORES | ATOFINA (FR) | 2000-08-24 | — | — | WO | disclosed |