Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 18/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1807533 | 0.84 | CHRNA7 (0.53) | — | |
| SCHEMBL1063085 | 0.83 | CCR3 (0.72) | MEN1KMT2A | |
| SCHEMBL30226931 | 0.78 | MAPK14 (0.64) | MGLL | |
| SCHEMBL22216445 | 0.78 | MAPK14 (0.64) | MGLLHSD11B1 | |
| SCHEMBL30329646 | 0.78 | MAPK14 (0.64) | MGLLHSD11B1 | |
| SCHEMBL8534513 | 0.78 | MAPK14 (0.64) | MGLL | |
| SCHEMBL3455621 | 0.78 | KDM4E (0.59) | MEN1KMT2A | |
| SCHEMBL22216202 | 0.78 | DRD2 (0.57) | MGLL | |
| SCHEMBL14559807 | 0.77 | GPR183 (0.54) | MGLL | |
| SCHEMBL3455562 | 0.77 | L3MBTL3 (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001056974-A2 | INHA INHIBITORS AND THEIR USE AS ANTIBACTERIALS | GENZYME CORPORATION (US) | 2001-08-09 | — | — | WO | claimed |
| US-6372752-B1 | ENZYME INHIBITORS, RESPIRATORY SYSTEM DISORDERS, TUBERCULOSIS AND MYCOBACTERIUM BACTERICIDES | GENZYME CORPORATION | 2002-04-16 | — | — | US | disclosed |