Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 5/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652040 | 0.82 | MAPT (0.57) | HTR2BTP53MAPTBCHEACHE | |
| SCHEMBL383213 | 0.82 | DRD4 (0.77) | KDM4EALDH1A1HPGD | |
| SCHEMBL383241 | 0.77 | MAPT (0.51) | HTR2BTP53MAPTRAB9AKDM4E | |
| SCHEMBL7651229 | 0.75 | TP53 (0.46) | HTR2BTP53MAPTBCHEACHE | |
| SCHEMBL2674037 | 0.75 | BCHE (0.90) | HTR2BTP53MAPTBCHEACHE | |
| SCHEMBL2676103 | 0.75 | BCHE (0.96) | HTR2BTP53MAPTBCHEACHE | |
| SCHEMBL23610369 | 0.74 | KDM4E (0.71) | TP53MAPTHDAC6RAB9AKDM4E | |
| SCHEMBL17737082 | 0.74 | KDM4E (0.71) | TP53MAPTHDAC6RAB9AKDM4E | |
| SCHEMBL2674838 | 0.74 | TP53 (1.00) | TP53MAPTBCHEACHEHTR3A | |
| SCHEMBL5309716 | 0.74 | BCHE (0.71) | HTR2BTP53MAPTBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451800-B1 | Phenylpiperazine derivatives as integrin αvβ3 antagonists | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-09-17 | — | — | US | disclosed |
| EP-1057818-A1 | PHENYLPIPERAZINE DERIVATIVES AS INTEGRIN ALPHAvBETA3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2000-12-06 | — | — | EP | disclosed |