Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253180 | 0.83 | GAA (0.49) | SMN1; SMN2LMNAMAPTMAPK1TRPM8 | |
| SCHEMBL3595140 | 0.80 | MAPT (0.48) | SMN1; SMN2LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL7651562 | 0.80 | MAPT (0.53) | SMN1; SMN2LMNAMAPTMAPK1TRPM8 | |
| SCHEMBL11499255 | 0.80 | GAA (0.46) | SMN1; SMN2LMNAMAPTTRPM8MEN1 | |
| SCHEMBL8491910 | 0.80 | KDM4E (0.59) | LMNAMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL29852705 | 0.79 | MAPT (0.64) | SMN1; SMN2LMNAMAPTMAPK1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27803914 | 0.78 | MAPT (0.48) | LMNAMAPTMAPK1TRPM8MEN1 | |
| SCHEMBL4193609 | 0.78 | MAPK1 (0.49) | SMN1; SMN2LMNAMAPTMAPK1TRPM8 | |
| SCHEMBL13869175 | 0.78 | PTGS1 (0.46) | MAPTALDH1A1KDM4ETDP1HSD17B10 | |
| SCHEMBL21973538 | 0.78 | PTGS1 (0.46) | MAPTALDH1A1KDM4ETDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407120-B1 | ADMINISTERING PYRIDINYLACETAMIDE OR PHENYLACETAMIDE DERIVATIVE TO TREAT CARDIOVASCULAR, EATING, SEXUAL, BRAIN, NERVOUS SYSTEM, GASTROINTESTINAL, UROGENITAL, PSYCHOLOGICAL, AND RESPIRATORY SYSTEM DISORDERS | PFIZER INC. | 2002-06-18 | — | — | US | disclosed |
| EP-1033366-A2 | Amide derivatives useful as Neuropeptide Y (NPY) antagonists | Pfizer Products Inc. (US) | 2000-09-06 | — | — | EP | disclosed |