SCHEMBL7651618

SCHEMBL7651618

CC(C)=CCc1cccc2oc(-c3ccccc3)c(O)c(=O)c12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.59
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
KDM4E B2RXH2 4/20 0.59
MAPT P10636 3/20 0.59
LMNA P02545 2/20 0.59
TP53 P04637 2/20 0.59
ALOX15 P16050 2/20 0.59
MAPK1 P28482 2/20 0.59
HPGD P15428 2/20 0.59
HSD17B10 Q99714 2/20 0.59
USP2 O75604 1/20 0.59
CYP19A1 P11511 3/20 0.55
ABCB1 P08183 4/20 0.54
PTPN1 P18031 1/20 0.54
MGAM O43451 1/20 0.53
CA12 O43570 2/20 0.51
CYP1B1 Q16678 2/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31571483 1.00 CYP3A4 (0.59) CYP3A4MEN1KMT2AKDM4EMAPT
SCHEMBL27631295 0.84 CYP3A4 (0.68) CYP3A4MEN1KMT2AKDM4EMAPT
SCHEMBL5274419 0.84 CYP3A4 (0.60) CYP3A4MEN1KMT2AKDM4EMAPT
SCHEMBL15899627 0.81 ABCG2 (0.54) CYP3A4MEN1KMT2AKDM4EMAPT
SCHEMBL3898402 0.80 ABCB1 (0.57) CYP3A4MEN1KMT2AKDM4EMAPT
SCHEMBL5072293 0.80 MGAM (0.74) CYP3A4MEN1KMT2AKDM4EMAPT
SCHEMBL28343536 0.79 CYP3A4 (0.58) CYP3A4MEN1KMT2AKDM4EMAPT
SCHEMBL28252602 0.79 CYP3A4 (0.60) CYP3A4MEN1KMT2AKDM4EMAPT
SCHEMBL2052448 0.78 IKBKB (0.58) CYP3A4KDM4EMAPTHPGDHSD17B10
SCHEMBL7047705 0.78 CYP3A4 (0.59) CYP3A4MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114796194-A Application of DA adduct derived from Morus plant in preparation of beta-G inhibitor 澳门大学 2022-07-29 CN claimed
CN-110872267-A Compound extracted from paper mulberry and application of compound in preparation of protein tyrosine phosphatase 1B inhibitor 复旦大学 2020-03-10 CN claimed
CN-114796194-B Application of DA adducts derived from Morus plants 澳门大学 2024-05-10 CN disclosed
CN-115364089-B Application of sanggenon C in preparation of medicine for treating glioblastoma 西南大学 2023-10-17 CN disclosed
US-20230190852-A1 COMPOSITIONS AND METHODS FOR JOINT HEALTH UNIGEN, INC. (US) 2023-06-22 US disclosed
CN-115950978-A Method for identifying flavonol novel compound in epimedium secondary metabolic pathway 重庆市中药研究院 2023-04-11 CN disclosed
CN-115364089-A Application of sanggenon C in preparing medicine for treating glioblastoma 西南大学 2022-11-22 CN disclosed
CN-114796194-A Application of DA adduct derived from Morus plant in preparation of beta-G inhibitor 澳门大学 2022-07-29 CN disclosed
CN-110872267-B Compound extracted from paper mulberry and application of compound in preparation of protein tyrosine phosphatase 1B inhibitor 复旦大学 2022-07-08 CN disclosed
CN-109207450-B Flavonoid isopentenyl transferase gene and application thereof 中国农业科学院北京畜牧兽医研究所 2022-04-15 CN disclosed
US-11123393-B2 Compositions and methods for joint health UNIGEN, INC. (US) 2021-09-21 US disclosed
CN-110872267-A Compound extracted from paper mulberry and application of compound in preparation of protein tyrosine phosphatase 1B inhibitor 复旦大学 2020-03-10 CN disclosed
EP-3010928-A1 COMPOSITIONS AND METHODS FOR JOINT HEALTH Unigen, Inc. (US) 2016-04-27 EP disclosed
US-20160067296-A1 Compositions and Methods for Joint Health UNIGEN, INC. (US) 2016-03-10 US disclosed
US-20150072953-A1 COMPOSITIONS AND METHODS FOR JOINT HEALTH UNIGEN, INC. 2015-03-12 US disclosed
WO-2014204866-A1 COMPOSITIONS AND METHODS FOR JOINT HEALTH UNIGEN, INC. (US) 2014-12-24 WO disclosed
US-6399579-B1 SOLVENT EXTRACTION; PLANT EXTRACTS HAUSER, INC. 2002-06-04 US disclosed
WO-2002013842-A1 COMPOSITIONS COMPRISING ICARISIDE I AND ANHYDROICARITIN AND METHODS FOR MAKING THE SAME HAUSER, INC. (US) 2002-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150072953-A1 COMPOSITIONS AND METHODS FOR JOINT HEALTH PTGES, PTGES3, PTGES2 CYP3A4 1888/4885MEN1 3730/4885KMT2A 3613/4885
US-11123393-B2 Compositions and methods for joint health PTGES, PTGES3, PTGES2 CYP3A4 1888/4885MEN1 3730/4885KMT2A 3613/4885
US-20160067296-A1 Compositions and Methods for Joint Health PTGES, PTGES3, PTGES2 CYP3A4 1888/4885MEN1 3730/4885KMT2A 3613/4885
US-20230190852-A1 COMPOSITIONS AND METHODS FOR JOINT HEALTH PTGES, PTGES3, PTGES2 CYP3A4 1888/4885MEN1 3730/4885KMT2A 3613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.