Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.58 |
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 6/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | XPO1 | O14980 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130212 | 0.85 | IKBKB (0.61) | IKBKBVKORC1MAOACYP19A1KDM4E | |
| SCHEMBL4452636 | 0.84 | MGAM (0.60) | IKBKBMAOACYP19A1PGAM1NUDT1 | |
| SCHEMBL28194247 | 0.81 | MAOA (0.53) | IKBKBMAOACYP17A1CYP19A1CYP11B1 | |
| SCHEMBL18242476 | 0.80 | MAOA (0.59) | MAOACYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL13359234 | 0.80 | MAOA (0.64) | MAOACYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL27726953 | 0.79 | MAOA (0.55) | MAOACYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7651618 | 0.78 | CYP3A4 (0.59) | VKORC1MAOACYP19A1KDM4EALDH1A1 | |
| SCHEMBL26671345 | 0.78 | MGAM (0.46) | MAOACYP19A1XPO1KDM4EALDH1A1 | |
| SCHEMBL31571483 | 0.78 | CYP3A4 (0.59) | VKORC1MAOACYP19A1KDM4EALDH1A1 | |
| SCHEMBL24075575 | 0.77 | NUDT1 (0.77) | IKBKBVKORC1MAOACYP19A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114796188-A | Plant-derived flavone antibacterial compound and application thereof | 朱奎 | 2022-07-29 | — | — | CN | claimed |
| CN-112569223-A | Plant-derived flavone antibacterial compound and application thereof | 朱奎 | 2021-03-30 | — | — | CN | claimed |
| CN-101550125-A | Hazelnut element B, extracting method and pharmaceutical use thereof | UNIV JILIN (CN) | 2009-10-07 | — | — | CN | claimed |
| EP-1824442-A1 | PHARMACEUTICAL AND THERAPEUTIC COMPOSITIONS DERIVED FROM GARCINIA MANGOSTANA L PLANT | Renaissance Herbs, Inc. (US) | 2007-08-29 | — | — | EP | claimed |
| WO-2007002666-A2 | PHARMACEUTICAL AND THERAPEUTIC COMPOSTIONS DERIVED FROM GARCINIA MANGOSTANA L PLANT | RENAISSANCE HERBS, INC. (US) | 2007-01-04 | — | — | WO | claimed |
| US-20060292255-A1 | Pharmaceutical and therapeutic compositions derived from Garcinia mangostana L plant | RENAISSSANCE HERBS INC. | 2006-12-28 | — | — | US | claimed |
| WO-2006055688-A1 | PHARMACEUTICAL AND THERAPEUTIC COMPOSITIONS DERIVED FROM GARCINIA MANGOSTANA L PLANT | RENAISSANCE HERBS, INC. (US) | 2006-05-26 | — | — | WO | claimed |
| US-20060105069-A1 | Pharmaceutical and therapeutic compositions derived from Garcinia mangostana L plant | RENAISSANCE HERBS, INC. | 2006-05-18 | — | — | US | claimed |
| US-20050118219-A1 | Methods for improving the aesthetic appearance of skin | CITIBANK, N.A., LONDON BRANCH | 2005-06-02 | — | — | US | claimed |
| US-20030138467-A1 | Methods for improving the aesthetic appearance of skin | AVON PRODUCTS, INC. (US) | 2003-07-24 | — | — | US | claimed |
| CN-119912472-A | Isopentenyl xanthone compound, and preparation method and application thereof | 湖北天勤生物技术研究院有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-117064875-A | Application of mangostin in preparation of drugs for preventing or treating amyotrophic lateral sclerosis | 上海交通大学医学院 | 2023-11-17 | — | — | CN | disclosed |
| CN-111349397-B | Pale rosin and rosin ester compositions | 科腾聚合物有限责任公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-113816936-B | Mangostin derivative compound and preparation method and application thereof | 广州长峰生物技术有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110799598-B | Light-colored rosin ester composition and preparation method thereof | 科腾聚合物有限责任公司 | 2022-03-29 | — | — | CN | disclosed |
| EP-1824442-A1 | PHARMACEUTICAL AND THERAPEUTIC COMPOSITIONS DERIVED FROM GARCINIA MANGOSTANA L PLANT | Renaissance Herbs, Inc. (US) | 2007-08-29 | — | — | EP | disclosed |
| WO-2007002666-A2 | PHARMACEUTICAL AND THERAPEUTIC COMPOSTIONS DERIVED FROM GARCINIA MANGOSTANA L PLANT | RENAISSANCE HERBS, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060292255-A1 | Pharmaceutical and therapeutic compositions derived from Garcinia mangostana L plant | RENAISSSANCE HERBS INC. | 2006-12-28 | — | — | US | disclosed |
| WO-2006055688-A1 | PHARMACEUTICAL AND THERAPEUTIC COMPOSITIONS DERIVED FROM GARCINIA MANGOSTANA L PLANT | RENAISSANCE HERBS, INC. (US) | 2006-05-26 | — | — | WO | disclosed |
| US-20060105069-A1 | Pharmaceutical and therapeutic compositions derived from Garcinia mangostana L plant | RENAISSANCE HERBS, INC. | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050118219-A1 | Methods for improving the aesthetic appearance of skin | CUTA, GLA, LRAT | IKBKB 3064/4885VKORC1 2927/4885MAOA 48/4885 |
| US-20030138467-A1 | Methods for improving the aesthetic appearance of skin | CUTA, GLA, LRAT | IKBKB 3064/4885VKORC1 2927/4885MAOA 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.