Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 12/20 | 0.51 |
| ▸ | EDNRA | P25101 | 12/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357632 | 0.82 | EDNRB (0.50) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL9723564 | 0.79 | EDNRB (0.48) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL15435730 | 0.79 | EDNRB (0.51) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL7652512 | 0.79 | HTT (0.49) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL9367122 | 0.78 | EDNRB (0.61) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL9723559 | 0.75 | EDNRB (0.55) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL9874421 | 0.74 | KMT2A (0.48) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL7006265 | 0.72 | KMT2A (0.53) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL9357252 | 0.72 | SMN1; SMN2 (0.49) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL12871107 | 0.72 | POLB (0.39) | EDNRBEDNRANR1I2KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482947-B1 | Substituted (hetero) aryl compounds, process for their preparation, agents containing them and their use as safeners | HOECHST AKTIENGESELLSCHAFT (DE) | 2002-11-19 | — | — | US | claimed |