Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655660 | 0.88 | LSS (0.48) | LSSSMN1; SMN2GBA1F10F2 | |
| SCHEMBL7651810 | 0.81 | LSS (0.63) | LSSSMN1; SMN2GBA1F10KDM4E | |
| SCHEMBL6182258 | 0.76 | LSS (1.00) | LSSF10PKMALDH1A1 | |
| SCHEMBL7655628 | 0.75 | HRH4 (0.45) | LSSF10 | |
| Hydrochloric Acid SCHEMBL7688789 | 0.74 | HRH4 (0.44) | LSSF10 | |
| SCHEMBL6977387 | 0.74 | LSS (0.76) | LSSSMN1; SMN2GBA1KDM4EMEN1 | |
| SCHEMBL8118785 | 0.74 | F10 (0.48) | LSSF10 | |
| SCHEMBL7682080 | 0.74 | LSS (0.54) | LSSGBA1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7050686 | 0.73 | F10 (0.47) | LSSF10 | |
| SCHEMBL6977994 | 0.73 | LSS (0.93) | LSSHPGDPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335341-B1 | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2002-01-01 | — | — | US | disclosed |