Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 3/20 | 0.63 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655662 | 0.89 | LSS (0.49) | LSSF10GBA1KMT2AMEN1 | |
| SCHEMBL7651807 | 0.81 | LSS (0.61) | LSSF10GBA1SMN1; SMN2KMT2A | |
| SCHEMBL6182258 | 0.77 | LSS (1.00) | LSSF10LMNAMAPK1ALDH1A1 | |
| SCHEMBL8309729 | 0.76 | LSS (0.89) | LSSF10LMNAMAPK1ALDH1A1 | |
| SCHEMBL6977387 | 0.76 | LSS (0.76) | LSSGBA1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6977994 | 0.74 | LSS (0.93) | LSSALDH1A1HPGD | |
| SCHEMBL6977537 | 0.74 | LSS (0.93) | LSSSMN1; SMN2KDM4ELMNAMAPK1 | |
| SCHEMBL8310078 | 0.73 | LSS (0.83) | LSSSMN1; SMN2LMNAMAPK1ALDH1A1 | |
| SCHEMBL7682080 | 0.73 | LSS (0.54) | LSSGBA1KMT2AMEN1KDM4E | |
| SCHEMBL6978604 | 0.72 | LSS (0.71) | LSSGBA1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335341-B1 | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2002-01-01 | — | — | US | disclosed |