Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657631 | 0.88 | CYP1A1 (0.43) | NR1H4ABCG2CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL7656619 | 0.86 | AURKA (0.48) | NR1H4ABCG2ARMAOBCYP2C9 | |
| SCHEMBL7652711 | 0.81 | ABCG2 (0.60) | ABCG2MAOBCYP2C19MAPTMEN1 | |
| SCHEMBL7662659 | 0.81 | MAPT (0.50) | NR1H4ABCG2MAOBCYP2C9CYP2C19 | |
| SCHEMBL7664550 | 0.78 | MAPT (0.43) | ARMAOBMAPTNPC1RAB9A | |
| SCHEMBL7664988 | 0.77 | AR (0.52) | ARMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL7666145 | 0.77 | MAOB (0.58) | ARMAOBCYP2C19MAPTNPSR1 | |
| SCHEMBL7661260 | 0.77 | MAOB (0.41) | CYP1A1CYP1B1CYP1A2GPR52AR | |
| SCHEMBL7657806 | 0.75 | AR (0.51) | ARMAOBMAPTMEN1KMT2A | |
| SCHEMBL7664261 | 0.75 | AR (0.39) | ABCG2ARMAOBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500846-B1 | 2-(4-CHLOROPHENYL)-7-METHOXYCHROMEN-4-ONE, AS CYCLIN-DEPENDENT KINASE INHIBITORS, USED AS ANTICARCINOGENIC AGENTS OR FOR PROPHYLAXIS OF NEURODEGENERATIVE DISEASE | LG CHEMICAL, LTD. (KR) | 2002-12-31 | — | — | US | disclosed |