Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7642619 | 1.00 | GSR (0.32) | GSRTXNRD1KDM4ENPSR1L3MBTL1 | |
| SCHEMBL3282799 | 0.79 | PTGS2 (0.36) | KDM4ENPSR1L3MBTL1 | |
| SCHEMBL8878264 | 0.75 | TDP1 (0.35) | — | |
| SCHEMBL4753484 | 0.74 | KDM4E (0.35) | KDM4ENPSR1L3MBTL1 | |
| SCHEMBL29851211 | 0.71 | KCNH2 (0.35) | KDM4ENPSR1L3MBTL1PTGER4 | |
| SCHEMBL2650003 | 0.71 | KCNH2 (0.35) | KDM4ENPSR1L3MBTL1PTGER4 | |
| SCHEMBL15561436 | 0.70 | CCR4 (0.34) | — | |
| SCHEMBL5719359 | 0.70 | TLR8 (0.32) | — | |
| SCHEMBL29851334 | 0.70 | CCR4 (0.34) | — | |
| SCHEMBL28932799 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001782-A4 | 5,6-HETEROARYL-DIPYRIDO 2,3-$i(b):3',2'-$i(f)]AZEPINES AND THEIR USE IN THE PREVENTION OR TREATMENT OF HIV INFECTION | BOEHRINGER INGELHEIM PHARMA (US) | 2002-01-30 | — | — | EP | disclosed |
| EP-1001782-A1 | 5,6-HETEROARYL-DIPYRIDO 2,3-$i(b):3',2'-$i(f)]AZEPINES AND THEIR USE IN THE PREVENTION OR TREATMENT OF HIV INFECTION | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2000-05-24 | — | — | EP | disclosed |
| US-5919779-A | VIRICIDE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1999-07-06 | — | — | US | disclosed |
| WO-1999007379-A1 | 5,6-HETEROARYL-DIPYRIDO[2,3-b:3',2'-f]AZEPINES AND THEIR USE IN THE PREVENTION OR TREATMENT OF HIV INFECTION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1999-02-18 | — | — | WO | disclosed |