Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12502917 | 0.81 | P2RX7 (0.34) | KDM4ELMNACYP2D6CYP19A1CYP2C9 | |
| SCHEMBL5935645 | 0.79 | NAPRT (0.37) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL2083596 | 0.79 | TRIM24 (0.32) | SMN1; SMN2L3MBTL1TDP1GAAHTT | |
| SCHEMBL14120504 | 0.77 | APLNR (0.37) | KDM4ECYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL29479488 | 0.76 | KDM4E (0.33) | KDM4ELMNACYP2D6CYP19A1CYP2C9 | |
| SCHEMBL15913345 | 0.76 | KDM4E (0.33) | KDM4ELMNACYP2D6CYP19A1CYP2C9 | |
| SCHEMBL21552099 | 0.76 | LMNA (0.36) | KDM4ELMNASMN1; SMN2HTT | |
| SCHEMBL691136 | 0.76 | KDM4E (0.41) | KDM4ELMNASMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL7652331 | 0.74 | GSR (0.32) | KDM4EL3MBTL1NPSR1 | |
| SCHEMBL7642619 | 0.74 | GSR (0.32) | KDM4EL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |