Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656005 | 1.00 | CASR (0.46) | CASRSIGMAR1KMT2AOPRM1TDP1 | |
| SCHEMBL7661916 | 0.90 | CASR (0.50) | CASRKMT2AMAOBMTNR1AMTNR1B | |
| SCHEMBL7311626 | 0.84 | KMT2A (0.43) | CASRKMT2AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL30167310 | 0.84 | KMT2A (0.43) | CASRKMT2AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL620934 | 0.81 | CASR (0.52) | CASRSIGMAR1KMT2AMAOBMTNR1A | |
| SCHEMBL5181398 | 0.79 | KMT2A (0.49) | CASRKMT2AOPRM1L3MBTL1MTNR1A | |
| SCHEMBL7405335 | 0.79 | CASR (0.47) | CASRSIGMAR1KMT2AOPRM1TDP1 | |
| SCHEMBL7413751 | 0.79 | CASR (0.47) | CASRSIGMAR1KMT2AOPRM1TDP1 | |
| SCHEMBL7410294 | 0.78 | KMT2A (0.47) | CASRKMT2AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL3827110 | 0.78 | AOC3 (0.44) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358973-B1 | FOR THERAPY OF ALLERGIC OR INFLAMMATORY DISEASE | ZAMBON GROUP S.P.A. (IT) | 2002-03-19 | — | — | US | disclosed |