Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405335 | 1.00 | CASR (0.47) | CASRMTNR1AMTNR1BTAAR1OPRM1 | |
| SCHEMBL20052924 | 0.89 | CASR (0.51) | CASRMTNR1AMTNR1BTAAR1 | |
| SCHEMBL7412978 | 0.89 | CASR (0.51) | CASRMTNR1AMTNR1BTAAR1 | |
| SCHEMBL14244978 | 0.82 | HTR2A (0.53) | SIGMAR1HTR2A | |
| SCHEMBL5311110 | 0.81 | MTNR1A (0.62) | CASRMTNR1AMTNR1BTAAR1 | |
| SCHEMBL11081355 | 0.79 | AOC3 (0.54) | CASRMTNR1AMTNR1BTAAR1L3MBTL1 | |
| SCHEMBL7652332 | 0.79 | CASR (0.46) | CASRMTNR1AMTNR1BOPRM1SIGMAR1 | |
| SCHEMBL7656005 | 0.79 | CASR (0.46) | CASRMTNR1AMTNR1BOPRM1SIGMAR1 | |
| SCHEMBL5180963 | 0.78 | L3MBTL1 (0.49) | MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL7411654 | 0.78 | AOC3 (0.48) | CASRMTNR1AMTNR1BTAAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358973-B1 | FOR THERAPY OF ALLERGIC OR INFLAMMATORY DISEASE | ZAMBON GROUP S.P.A. (IT) | 2002-03-19 | — | — | US | disclosed |
| EP-1121353-A1 | BENZAZINE DERIVATIVES AS PHOSPHODIESTERASE 4 INHIBITORS | ZAMBON GROUP S.p.A. (IT) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021947-A1 | BENZAZINE DERIVATIVES AS PHOSPHODIESTERASE 4 INHIBITORS | ZAMBON GROUP S.P.A. (IT) | 2000-04-20 | — | — | WO | disclosed |