Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.47 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775717 | 0.83 | MAPT (0.53) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL3763449 | 0.83 | MAPT (0.53) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL29894089 | 0.78 | AKR1C3 (0.42) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL8067990 | 0.77 | MAPT (0.47) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL5068764 | 0.77 | KMT2A (0.71) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL5068765 | 0.77 | KMT2A (0.71) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL11319954 | 0.76 | MAPT (0.53) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL29169711 | 0.76 | AKR1C1 (0.46) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL30443858 | 0.75 | LMNA (0.45) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL4430391 | 0.75 | EGFR (0.47) | HDAC3HDAC4HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6488509-B1 | Plug filling for dual-damascene process | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY (TW) | 2002-12-03 | — | — | US | claimed |