SCHEMBL11319954

SCHEMBL11319954

C=CC(=O)OOC(=O)C=Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.53
LMNA P02545 3/20 0.53
ALDH1A1 P00352 3/20 0.53
HDAC3 O15379 2/20 0.53
HDAC4 P56524 2/20 0.53
HDAC1 Q13547 2/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC8 Q9BY41 2/20 0.53
HDAC6 Q9UBN7 2/20 0.53
PLIN1 O60240 2/20 0.53
RECQL P46063 2/20 0.53
PLIN5 Q00G26 2/20 0.53
ABHD5 Q8WTS1 2/20 0.53
F3 P13726 2/20 0.53
TNKS O95271 1/20 0.53
HCAR2 Q8TDS4 1/20 0.53
HDAC7 Q8WUI4 1/20 0.53
HDAC10 Q969S8 1/20 0.53
HDAC11 Q96DB2 1/20 0.53
TNKS2 Q9H2K2 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL869265 0.90 MAPT (0.64) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL869266 0.90 MAPT (0.64) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL775717 0.85 MAPT (0.53) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL3763449 0.85 MAPT (0.53) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL15950322 0.82 MAPT (0.59) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL474095 0.82 MAPT (0.59) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL5068765 0.82 KMT2A (0.71) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL5068764 0.82 KMT2A (0.71) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL843436 0.81 AKR1B10 (0.71) MAPTLMNAALDH1A1CYP1A2CYP2D6
SCHEMBL843435 0.81 AKR1B10 (0.71) MAPTLMNAALDH1A1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101918886-B Optical film, method of manufacturing the same, and liquid crystal display including the same LG CHEMICAL INC 2013-01-23 CN claimed
CN-101918885-B Optical film, preparation method of the same, and liquid crystal display comprising the same LG CHEMICAL LTD 2012-03-21 CN claimed
CN-101918886-A Optical film, method of manufacturing the same, and liquid crystal display including the same LG CHEMICAL LTD 2010-12-15 CN claimed
CN-101918885-A Optical film, preparation method of the same, and liquid crystal display comprising the same LG CHEMICAL LTD 2010-12-15 CN claimed
US-4251618-A COALESCIBLE POLYVINYL CHLORIDE POLYMER DISPERSION MODIFIED BY A PHOTOPOLYMERIZABLE OR PHOTOCROSSLINKABLE GROUP E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-02-17 US claimed
CN-101918886-B Optical film, method of manufacturing the same, and liquid crystal display including the same LG CHEMICAL INC 2013-01-23 CN disclosed
CN-101918885-B Optical film, preparation method of the same, and liquid crystal display comprising the same LG CHEMICAL LTD 2012-03-21 CN disclosed
CN-101918886-A Optical film, method of manufacturing the same, and liquid crystal display including the same LG CHEMICAL LTD 2010-12-15 CN disclosed
CN-101918885-A Optical film, preparation method of the same, and liquid crystal display comprising the same LG CHEMICAL LTD 2010-12-15 CN disclosed