Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652378 | 0.83 | TSHR (0.43) | TSHRERN1TLR2TLR1TLR6 | |
| SCHEMBL7652380 | 0.83 | TSHR (0.43) | TSHRERN1TLR2TLR1TLR6 | |
| SCHEMBL17755154 | 0.79 | TSHR (0.53) | TSHRKDM4ELMNAMEN1KMT2A | |
| SCHEMBL15705142 | 0.78 | TSHR (0.51) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL17755042 | 0.78 | CTSD (0.53) | TSHRLMNACA1CA2HSD17B10 | |
| SCHEMBL9510853 | 0.78 | TSHR (0.51) | TSHRKDM4ELMNAMEN1KMT2A | |
| SCHEMBL9510864 | 0.78 | TSHR (0.51) | TSHRKDM4ELMNAMEN1KMT2A | |
| SCHEMBL9184046 | 0.77 | ERN1 (0.44) | TSHRERN1TLR2TLR1TLR6 | |
| SCHEMBL121356 | 0.77 | LMNA (0.57) | TSHRKDM4ELMNAMEN1THRB | |
| SCHEMBL30635255 | 0.77 | LMNA (0.57) | TSHRKDM4ELMNAMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410600-B1 | CONTROLLING MICROORGANISMS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-25 | — | — | US | disclosed |