Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 6/20 | 0.75 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.75 |
| ▸ | HTR3B | O95264 | 4/20 | 0.75 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.75 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.75 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.75 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.69 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.69 |
| ▸ | CHRNG | P07510 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.69 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652481 | 1.00 | HTR3A (0.75) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL5789144 | 0.94 | HTR3A (0.68) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL5789139 | 0.94 | HTR3A (0.68) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL6507170 | 0.90 | HTR3E (0.66) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL5789101 | 0.90 | HTR3A (0.66) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL6507167 | 0.90 | HTR3E (0.66) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL5789103 | 0.90 | HTR3A (0.66) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Benzoyl Tropine SCHEMBL221830 | 0.86 | HTR3E (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Benzoyl Tropine SCHEMBL30954638 | 0.86 | HTR3E (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Benzoyl Tropine SCHEMBL1103723 | 0.86 | HTR3E (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376510-B1 | ADMINISTERING A ALKOXY- AND ACYLOXY-SUBSTITUTED ARALKYL AND ARALKENYL BIS QUATERNARY AMMONIUM DERIVATIVES OF CYCLIC ALKANOL DIESTERS TO A HUMAN AS MUSCLE RELAXANTS | NEWLAXANT LLC | 2002-04-23 | — | — | US | disclosed |
| US-6274757-B1 | REACTING AN HYDROXY AMINE CORRESPONDING COMPOUND WITH DICHLORO COMPOUND | NEWLAXANT LLC | 2001-08-14 | — | — | US | disclosed |