Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | AKT2 | P31751 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10179931 | 0.93 | MAPT (0.37) | MAPTLMNAHTTAKT2BRD4 | |
| SCHEMBL28163073 | 0.92 | BRD4 (0.35) | MAPTLMNAHTTAKT2BRD4 | |
| SCHEMBL19956857 | 0.83 | AKT2 (0.33) | MAPTLMNAHTTAKT2BRD4 | |
| SCHEMBL6294085 | 0.82 | LMNA (0.48) | MAPTLMNAHTTAKT2BRD4 | |
| SCHEMBL8618279 | 0.82 | LMNA (0.48) | MAPTLMNAHTTAKT2BRD4 | |
| SCHEMBL9701681 | 0.79 | LMNA (0.46) | MAPTLMNAHTTAKT2BRD4 | |
| SCHEMBL9701635 | 0.79 | LMNA (0.50) | MAPTLMNAHTTAKT2BRD4 | |
| SCHEMBL21531030 | 0.78 | MAPT (0.40) | MAPTLMNAHTTAKT2BRD4 | |
| SCHEMBL27619559 | 0.76 | LMNA (0.48) | MAPTLMNAHTTAKT2BRD4 | |
| SCHEMBL5145616 | 0.73 | LMNA (0.50) | MAPTLMNAHTTAKT2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002316975-A | TETRAMERCAPTOBIPHENYL AND METHOD FOR SYNTHESIZING THE SAME | JAPAN SCIENCE & TECHNOLOGY CORP | 2002-10-31 | — | — | JP | disclosed |