SCHEMBL9701681

SCHEMBL9701681

Cc1c(C)c(-c2ccccc2)c(C)c(-c2ccccc2)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
HTT P42858 2/20 0.46
ALDH1A1 P00352 1/20 0.44
AKT2 P31751 2/20 0.43
BRD4 O60885 2/20 0.43
CHEK1 O14757 1/20 0.43
BRD2 P25440 1/20 0.43
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
ACHE P22303 2/20 0.40
TDO2 P48775 1/20 0.40
TSHR P16473 1/20 0.40
ALOX12 P18054 1/20 0.40
KMT2A Q03164 1/20 0.40
SENP1 Q9P0U3 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PDE4A P27815 1/20 0.38
PDE4B Q07343 1/20 0.38
PDE4C Q08493 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8618279 0.97 LMNA (0.48) LMNAMAPTHTTALDH1A1AKT2
SCHEMBL9701635 0.94 LMNA (0.50) LMNAMAPTHTTALDH1A1AKT2
SCHEMBL5145616 0.94 LMNA (0.50) LMNAMAPTHTTALDH1A1AKT2
SCHEMBL6294085 0.91 LMNA (0.48) LMNAMAPTHTTALDH1A1AKT2
SCHEMBL27619559 0.85 LMNA (0.48) LMNAMAPTHTTALDH1A1AKT2
SCHEMBL9228160 0.85 LMNA (0.39) LMNAMAPTHTTALDH1A1AKT2
SCHEMBL28193538 0.83 SENP1 (0.46) LMNAMAPTHTTAKT2BRD4
SCHEMBL28883541 0.83 AKT2 (0.47) LMNAMAPTHTTALDH1A1AKT2
SCHEMBL25428412 0.81 AKT2 (0.50) LMNAMAPTHTTALDH1A1AKT2
SCHEMBL12348879 0.81 LMNA (0.45) LMNAMAPTHTTALDH1A1AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113583443-A Transparent polyimide applied to flexible photoelectric field and preparation method thereof 深圳瑞华泰薄膜科技股份有限公司 2021-11-02 CN disclosed
CN-1329778-C Double-layer positive electric performance organic light receptor SAMSUNG ELECTRONICS CO LTD (KR) 2007-08-01 CN disclosed
CN-1515964-A Double-layer positive electric performance organic light receptor ���ǵ�����ʽ���� 2004-07-28 CN disclosed
EP-0475676-A1 Electrophotographic member HITACHI CHEMICAL CO., LTD. (JP) 1992-03-18 EP disclosed
EP-0247731-B1 NOVEL PARA- OR META-TERPHENYLTETRACARBOXYLIC ACID, DIANHYDRIDE THEREOF AND PROCESS FOR PREPARING THE SAME Hitachi Chemical Co., Ltd. (JP) 1991-08-21 EP disclosed
EP-0247731-A1 Novel para- or meta-terphenyltetracarboxylic acid, dianhydride thereof and process for preparing the same Hitachi Chemical Co., Ltd. (JP) 1987-12-02 EP disclosed