Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652086 | 0.98 | NCEH1 (0.41) | NCEH1KCNA3MAPTPOLBKMT2A | |
| SCHEMBL7652659 | 0.95 | NCEH1 (0.43) | NCEH1KCNA3MAPTPOLBKMT2A | |
| SCHEMBL7649377 | 0.89 | MAPT (0.41) | NCEH1KCNA3MAPTPOLBKMT2A | |
| SCHEMBL7646969 | 0.82 | MAPT (0.43) | NCEH1KCNA3MAPTPOLBKMT2A | |
| SCHEMBL7649179 | 0.77 | HRH1 (0.39) | SLC6A4SLC2A1 | |
| SCHEMBL7654241 | 0.76 | HRH1 (0.38) | SLC6A4SLC2A1 | |
| SCHEMBL10473118 | 0.76 | MAPT (0.53) | KCNA3MAPTKMT2A | |
| SCHEMBL31573993 | 0.76 | L3MBTL1 (0.50) | NCEH1KCNA3MAPTPOLBKMT2A | |
| SCHEMBL7650726 | 0.76 | TSHR (0.47) | NCEH1MAPTKMT2ASLC6A4SLC2A1 | |
| SCHEMBL7651008 | 0.75 | MCL1 (0.38) | NCEH1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |