Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649377 | 0.86 | MAPT (0.41) | MAPTKCNA3HSD17B10KMT2AKDM4E | |
| SCHEMBL7652659 | 0.83 | NCEH1 (0.43) | MAPTKCNA3KMT2APOLBNCEH1 | |
| SCHEMBL7652685 | 0.82 | NCEH1 (0.42) | MAPTKCNA3KMT2APOLBNCEH1 | |
| SCHEMBL31573993 | 0.82 | L3MBTL1 (0.50) | MAPTKCNA3HSD17B10KMT2AKDM4E | |
| SCHEMBL10473118 | 0.82 | MAPT (0.53) | MAPTKCNA3HSD17B10KMT2AKDM4E | |
| SCHEMBL7652086 | 0.81 | NCEH1 (0.41) | MAPTKCNA3KMT2APOLBNCEH1 | |
| SCHEMBL25969601 | 0.79 | MAPT (0.61) | MAPTKCNA3HSD17B10KMT2AKDM4E | |
| SCHEMBL7654717 | 0.78 | MAPT (0.46) | MAPTKCNA3HSD17B10KMT2AKDM4E | |
| SCHEMBL1052575 | 0.76 | MAPT (0.52) | MAPTKCNA3HSD17B10KMT2AKDM4E | |
| SCHEMBL9319668 | 0.74 | PTPN22 (0.50) | MAPTHSD17B10CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |