Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 3/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659824 | 0.89 | IL6ST (0.45) | IL6STSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7654809 | 0.86 | IL6ST (0.43) | IL6STSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7656852 | 0.86 | IL6ST (0.43) | IL6STSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7652948 | 0.85 | IL6ST (0.42) | IL6STSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7652789 | 0.83 | IL6ST (0.42) | IL6STSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7653046 | 0.77 | IL6ST (0.44) | IL6STIDH1 | |
| SCHEMBL9556952 | 0.70 | IL6ST (0.60) | IL6STSTAT3IDH1 | |
| SCHEMBL9557166 | 0.70 | IL6ST (0.60) | IL6STSTAT3IDH1 | |
| SCHEMBL9556716 | 0.70 | IL6ST (0.60) | IL6STSTAT3IDH1 | |
| SCHEMBL9556794 | 0.70 | IL6ST (0.60) | IL6STSTAT3IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448409-B1 | ACYLATION OF AN 2-OXAZOLIDINESELONE WITH AN ALKYL ACYLHALIDE AND HYDROXYLATION WITH AN ALDEHYDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-09-10 | — | — | US | disclosed |