Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659824 | 0.84 | IL6ST (0.45) | IL6STSTAT3CYP2D6IDH1SLC1A3 | |
| SCHEMBL7654809 | 0.83 | IL6ST (0.43) | IL6STSTAT3CYP2D6ALDH1A1MAPK1 | |
| SCHEMBL7652797 | 0.83 | IL6ST (0.44) | IL6STSTAT3CYP2D6IDH1SLC1A3 | |
| SCHEMBL7652948 | 0.82 | IL6ST (0.42) | IL6STSTAT3CYP2D6IDH1SLC1A3 | |
| SCHEMBL7656852 | 0.81 | IL6ST (0.43) | IL6STCYP2D6SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7661064 | 0.74 | IL6ST (0.41) | IL6STSTAT3ALDH1A1IDH1 | |
| SCHEMBL7653046 | 0.73 | IL6ST (0.44) | IL6STALDH1A1IDH1MAPT | |
| SCHEMBL14503033 | 0.65 | ALDH1A1 (0.49) | ALDH1A1MAPK1MEN1KMT2AGLRA1 | |
| SCHEMBL7359508 | 0.63 | IL6ST (0.55) | IL6STSTAT3IDH1 | |
| SCHEMBL7359514 | 0.63 | IL6ST (0.55) | IL6STSTAT3IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448409-B1 | ACYLATION OF AN 2-OXAZOLIDINESELONE WITH AN ALKYL ACYLHALIDE AND HYDROXYLATION WITH AN ALDEHYDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-09-10 | — | — | US | disclosed |