Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655964 | 0.98 | CYP1A2 (0.47) | CYP1A2CYP2A6MAPTCYP2C19CYP3A4 | |
| SCHEMBL7654443 | 0.93 | CYP1A2 (0.48) | CYP1A2CYP2A6CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL1706604 | 0.86 | CYP1A2 (0.52) | CYP1A2CYP2A6CYP2C19CYP3A4CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL27919149 | 0.84 | MAPT (0.49) | CYP1A2CYP2A6MAPTCYP3A4TDP1 | |
| Ammonia Solution, Strong SCHEMBL27919173 | 0.84 | MAPT (0.49) | CYP1A2CYP2A6MAPTCYP3A4TDP1 | |
| SCHEMBL27471657 | 0.83 | CYP1A2 (0.48) | CYP1A2CYP2A6MAPTCYP3A4TDP1 | |
| SCHEMBL27477260 | 0.82 | CYP1A2 (0.59) | CYP1A2CYP2A6CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL7654083 | 0.80 | MAPT (0.40) | MAPTCYP3A4TLR8 | |
| Ammonia Solution, Strong SCHEMBL27938005 | 0.80 | CYP1A2 (0.48) | CYP1A2CYP2A6MAPTTDP1TLR8 | |
| SCHEMBL7649355 | 0.79 | CHRNA7 (0.37) | MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149214-C | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | ������������ʽ���� | 2004-05-12 | — | — | CN | disclosed |
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| CN-1293674-A | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2001-05-02 | — | — | CN | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |