Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.37 |
| ▸ | CHRNA10 | Q9GZZ6 | 4/20 | 0.37 |
| ▸ | CHRNA9 | Q9UGM1 | 4/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655581 | 0.98 | HTR6 (0.37) | CHRNA7CHRNA10CHRNA9MTNR1AMTNR1B | |
| SCHEMBL7647401 | 0.94 | HTR6 (0.38) | CHRNA7CHRNA10CHRNA9MTNR1AMTNR1B | |
| SCHEMBL7649102 | 0.87 | HTR6 (0.40) | MTNR1AMTNR1BHTR6MAPTTACR3 | |
| SCHEMBL27550729 | 0.83 | MAPT (0.46) | MTNR1AMTNR1BMAPTTACR3KDM4E | |
| SCHEMBL7650707 | 0.80 | HTR6 (0.41) | MTNR1AMTNR1BHTR6MAPTTACR3 | |
| SCHEMBL7652962 | 0.79 | CYP1A2 (0.46) | MAPTTDP1 | |
| SCHEMBL7654083 | 0.79 | MAPT (0.40) | MTNR1AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL7652971 | 0.78 | ESR1 (0.34) | MAPTKDM4EKMT2A | |
| SCHEMBL7763131 | 0.78 | NQO2 (0.47) | MAPTKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL7655964 | 0.78 | CYP1A2 (0.47) | MAPTMEN1KMT2ASIGMAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| CN-1293674-A | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2001-05-02 | — | — | CN | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |