Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.45 |
| ▸ | HTR2C | P28335 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | HTR1D | P28221 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR1E | P28566 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1337678 | 0.81 | HTR1A (0.38) | HTR2AHTR2CHTR1AHTR2BHTR1D | |
| SCHEMBL3483410 | 0.77 | MEN1 (0.41) | HTR2AHTR2CHTR1AHTR2BHTR1D | |
| SCHEMBL440951 | 0.77 | HTR2A (0.40) | HTR2AHTR2CHTR1AHTR2BHTR1D | |
| SCHEMBL827572 | 0.75 | HTR2A (0.74) | HTR2AHTR2CHTR1AHTR2BHTR1D | |
| SCHEMBL15515402 | 0.75 | CSNK2A1 (0.55) | HTR2AHTR2CHTR1DHTR1BSLC6A4 | |
| SCHEMBL27851522 | 0.75 | HTR2A (0.59) | HTR2AHTR2CHTR1AHTR2BHTR1D | |
| SCHEMBL15515563 | 0.75 | HTR2C (0.54) | HTR2AHTR2CHTR1AHTR2BHTR1D | |
| SCHEMBL9232580 | 0.74 | HTR2A (0.62) | HTR2AHTR2CHTR1AHTR2BHTR1D | |
| SCHEMBL5814891 | 0.72 | HTR2A (0.44) | HTR2AHTR2CHTR1AHTR2BHTR1D | |
| SCHEMBL19067627 | 0.71 | HTR2A (0.61) | HTR2AHTR2CHTR1AHTR2BHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492394-B1 | PROCOLLAGEN C-PROTEINASE INHIBITORS; TREATING FIBROTIC DISEASES | SYNTEX (U.S.A.) LLC | 2002-12-10 | — | — | US | disclosed |