Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616065 | 0.82 | — | — | |
| SCHEMBL22764842 | 0.81 | — | — | |
| SCHEMBL24092186 | 0.77 | TSHR (0.32) | — | |
| SCHEMBL11231613 | 0.77 | — | — | |
| SCHEMBL3638444 | 0.77 | — | — | |
| SCHEMBL3638443 | 0.77 | — | — | |
| SCHEMBL22065221 | 0.74 | — | — | |
| SCHEMBL20866818 | 0.74 | — | — | |
| SCHEMBL20340973 | 0.72 | LMNA (0.40) | — | |
| SCHEMBL13767323 | 0.71 | ZDHHC20 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064396-A9 | NOVEL EZRIN INHIBITORS AND METHODS OF MAKING AND USING | GEORGETOWN UNIVERSITY (US) | 2012-07-05 | — | — | WO | disclosed |
| WO-2012064396-A2 | NOVEL EZRIN INHIBITORS AND METHODS OF MAKING AND USING | GEORGETOWN UNIVERSITY (US) | 2012-05-18 | — | — | WO | disclosed |