Acetic Acid

Acetic Acid

SCHEMBL7653168

CC(=O)O.N=C(N)c1ccc(N2CCN(CC(=O)NC(CC(=O)O)c3ccccn3)C(=O)C2)cc1

nearest known ligand 0.43

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 19/20 0.43
ITGA2B P08514 19/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7455137 0.98 ITGB3 (0.43) ITGB3ITGA2B
Acetic Acid SCHEMBL7665575 0.91 ITGB3 (0.38) ITGB3ITGA2B
SCHEMBL7651092 0.83 EP300 (0.44) ITGB3ITGA2B
SCHEMBL7651100 0.79 ITGB3 (0.36) ITGB3ITGA2B
SCHEMBL7651103 0.79 ITGB3 (0.36) ITGB3ITGA2B
SCHEMBL7447248 0.79 ITGB3 (0.46) ITGB3ITGA2B
SCHEMBL7662823 0.78 F10 (0.36)
SCHEMBL7662828 0.78 F10 (0.36)
SCHEMBL7449631 0.78 ITGB3 (0.45) ITGB3ITGA2B
SCHEMBL7451002 0.77 ITGB3 (0.48) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6344456-B1 ANTICOAGULANTS LABORATOIRE L. LAFON (FR) 2002-02-05 US disclosed