SCHEMBL7653199

SCHEMBL7653199

CCCc1oc(-c2ccc(-c3ccccc3)cc2)nc1CCOc1ccc(OC(C)(C)C)cc1

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 20/20 0.60
PPARG P37231 16/20 0.60
PPARD Q03181 9/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6696876 0.90 PPARA (0.76) PPARAPPARGPPARD
SCHEMBL5105781 0.87 PPARA (0.76) PPARAPPARGPPARD
SCHEMBL6700759 0.87 PPARA (0.64) PPARAPPARGPPARD
SCHEMBL5103186 0.84 PPARA (0.64) PPARAPPARGPPARD
SCHEMBL6993359 0.81 PPARA (0.69) PPARAPPARGPPARD
SCHEMBL6603469 0.76 PPARG (0.60) PPARAPPARGPPARD
SCHEMBL6701063 0.76 PPARA (0.82) PPARAPPARGPPARD
SCHEMBL6695462 0.75 PPARA (1.00) PPARAPPARGPPARD
SCHEMBL4035427 0.75 FFAR1 (0.56) PPARAPPARGPPARD
SCHEMBL6583439 0.75 MAPT (0.54) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6417212-B1 PHENYLOXAZOLE SUBSTITUTED ON BENZENEOXYPROPIONIC ACID OR ESTERS ELI LILLY & COMPANY 2002-07-09 US disclosed