Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030444 | 0.98 | ABCC4 (0.52) | ABCC4MAPTLMNATSHRNFKB1 | |
| Pimelic Acid SCHEMBL27489739 | 0.98 | ABCC4 (0.52) | ABCC4MAPTLMNATSHRNFKB1 | |
| Sebacic Acid SCHEMBL27800153 | 0.98 | ABCC4 (0.52) | ABCC4MAPTLMNATSHRNFKB1 | |
| SCHEMBL27757682 | 0.98 | ABCC4 (0.52) | ABCC4MAPTLMNATSHRNFKB1 | |
| Azelaic Acid SCHEMBL28182110 | 0.98 | ABCC4 (0.52) | ABCC4MAPTLMNATSHRNFKB1 | |
| Glutarate SCHEMBL28104234 | 0.96 | SLC22A6 (0.48) | ABCC4MAPTLMNATSHRNFKB1 | |
| Hexanoate SCHEMBL11160574 | 0.92 | AKR1B1 (0.59) | MAPTLMNATSHRGPR84FFAR1 | |
| Succinic Acid SCHEMBL4123721 | 0.91 | LMNA (0.46) | ABCC4MAPTLMNATSHRNFKB1 | |
| Stearic Acid SCHEMBL1768854 | 0.91 | GPR84 (0.61) | MAPTLMNATSHRGPR84FFAR1 | |
| Tridecanoate SCHEMBL27326028 | 0.91 | GPR84 (0.61) | MAPTLMNATSHRGPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103173020-B | High reliability curable silicone resin composition and the luminescent semiconductor device using said composition | 信越化学工业株式会社 | 2017-03-01 | — | — | CN | disclosed |
| CN-105849955-A | Binder composition for lithium ion secondary battery electrode, and lithium ion secondary battery | 日本合成化学工业株式会社 | 2016-08-10 | — | — | CN | disclosed |
| CN-103173020-A | Curable silicone resin composition with high reliability and optical semiconductor device using same | SHINETSU CHEMICAL CO | 2013-06-26 | — | — | CN | disclosed |
| US-6492444-B1 | FLAME RETARDANT ORGANIC PHOSPHORUS-PHOSPHORUS OXYACID COMPOUNDS ARE PRODUCED BY MIXING AND REACTING A PHOSPHORUS HALIDE, PHOSPHORUS OXYACID AND AN ORGANIC COMPOUND TO FORM ORGANIC PHOSPHORUS-PHSPHORUS OXYACID AND/OR SALTS | BLOUNT DAVID H (US) | 2002-12-10 | — | — | US | disclosed |
| US-6054515-A | FIRE RETARDANT: NITROGEN SALT OF ORGANIC POLYPHOSPHOROUS OXYACID PRODUCED BY REACTING A CYCLIC PHOSPHONATE ESTER, INORGANIC PHOSPHORUS OXYACID, AND NITROGEN COMPOUND; ALSO CONTAINS COMB POLYMER, CARBONIZATION ACCELERATER, AND FILLER | BLOUNT DAVID H (US) | 2000-04-25 | — | — | US | disclosed |