Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654451 | 0.89 | KDM4E (0.43) | KDM4EMEN1KMT2ANPSR1LMNA | |
| SCHEMBL11242524 | 0.83 | NOX1 (0.45) | SMN1; SMN2NOX1LMNAMAPTMAPK1 | |
| SCHEMBL7650131 | 0.82 | SMN1; SMN2 (0.46) | KDM4EMEN1KMT2ASMN1; SMN2NOX1 | |
| SCHEMBL7654647 | 0.78 | SMN1; SMN2 (0.40) | KDM4EMEN1KMT2ASMN1; SMN2NOX1 | |
| SCHEMBL7655919 | 0.75 | FERMT2 (0.52) | SMN1; SMN2NOX1MAPTGAA | |
| SCHEMBL7655772 | 0.75 | SMN1; SMN2 (0.48) | KDM4EMEN1KMT2ASMN1; SMN2NOX1 | |
| SCHEMBL7655830 | 0.75 | SMN1; SMN2 (0.44) | KDM4EMEN1KMT2ASMN1; SMN2NOX1 | |
| SCHEMBL7657018 | 0.75 | NSD2 (0.44) | KDM4EMEN1KMT2ASMN1; SMN2NOX1 | |
| Bromide SCHEMBL7657001 | 0.74 | SMN1; SMN2 (0.43) | KDM4EMEN1KMT2ASMN1; SMN2NOX1 | |
| SCHEMBL11864091 | 0.74 | MAPK1 (0.44) | KDM4EMEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340687-B1 | ELEVATE HIGH DENSITY LIPOPROTEIN CHOLESTEROL CONCENTRATION | AMERICAN HOME PRODUCTS CORPORATION | 2002-01-22 | — | — | US | disclosed |