Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648396 | 0.76 | BAX (0.47) | MAPT | |
| SCHEMBL608957 | 0.76 | CCR1 (0.47) | CNR1CCR1THRBMAPTLMNA | |
| SCHEMBL607458 | 0.76 | RAD52 (0.66) | MAPTLMNAMEN1RAD52KMT2A | |
| SCHEMBL607028 | 0.72 | MEN1 (0.76) | MAPTLMNAMEN1RAD52KMT2A | |
| SCHEMBL608135 | 0.71 | RAD52 (0.48) | CNR1CCR1MAPTLMNAMEN1 | |
| SCHEMBL6363590 | 0.69 | MAPT (0.61) | CNR1MAPTLMNAMAPK8MEN1 | |
| SCHEMBL7652515 | 0.66 | MAPT (0.53) | MAPTLMNAMEN1RAD52KMT2A | |
| SCHEMBL1696714 | 0.64 | CNR2 (0.41) | CNR1MAPTLMNAMEN1RAD52 | |
| SCHEMBL22439063 | 0.63 | ICMT (0.48) | CNR1MAPK8 | |
| SCHEMBL22439157 | 0.62 | ICMT (0.48) | CNR1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237887-A1 | 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001029028-A1 | 9- (PIPERAZINYLALKYL) CARBAZOLES AS BAX-MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-26 | — | — | WO | disclosed |